FITC标记的低密度脂蛋白受体相关蛋白11抗体
产品名称： FITC标记的低密度脂蛋白受体相关蛋白11抗体
英文名称： Anti-LRP11/FITC
产品编号： HZ-18361R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LRP11/FITC Conjugated antibody
FITC标记的低密度脂蛋白受体相关蛋白11抗体
| 英文名称 | Anti-LRP11/FITC |
| 中文名称 | FITC标记的低密度脂蛋白受体相关蛋白11抗体 |
| 别 名 | bA350J20.3; Low density lipoprotein receptor related protein 11; LRP 11; MANSC3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LRP11 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: LRP11 is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms. LRP11 is encoded by a gene located on human chromosome 6q25.1. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Function: LRP11 belongs to the LDLR family. It contains one LDL-receptor class A domain, one MANEC domain and one PKD domain. There are two named isoforms. Subcellular Location: Membrane; Single pass type I membrane protein Similarity: Belongs to the LDLR family. Contains 1 LDL-receptor class A domain. Contains 1 MANSC domain. Contains 1 PKD domain. Database links: Entrez Gene: 84918 Human SwissProt: Q86VZ4 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
LRP11是一种500氨基酸单通道I型膜蛋白，以两种交替剪接的异构体存在。LRP11由位于人类染色体6q25.1上的基因编码。第6染色体包含1亿7000万个碱基对，并包含人类基因组的近6%。6号染色体q臂部分缺失与早期发病的肠癌有关，提示存在癌症易感位点。此外，迟发性皮肤卟啉症、帕金森病、Stickler综合征和双相情感障碍的易感性都与映射到6号染色体的基因有关。