ARID3A抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ARID3A抗体

ARID3A抗体

商家询价

产品名称: ARID3A抗体

英文名称: ARID3AAntibody

产品编号: XY14068-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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 ARID3A抗体

Applications
In-house applications ELISA, WB, IHC, IF, IP     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 14068-1-AP;K-562 cellsK-562 cells were subjected to SDS PAGE followed by western blot with 14068-1-AP(ARID3A antibody) at dilution of 1:1500
  • 14068-1-AP;human colon cancerImmunohistochemical of paraffin-embedded human colon cancer using 14068-1-AP(ARID3A antibody) at dilution of 1:100 (under 10x lens)
  • 14068-1-AP;human colon cancerImmunohistochemical of paraffin-embedded human colon cancer using 14068-1-AP(ARID3A antibody) at dilution of 1:100 (under 40x lens)
  • 14068-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using ARID3A antibody 14068-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
  • 14068-1-AP;K-562 cellsIP Result of anti-ARID3A (IP:14068-1-AP, 4ug; Detection:14068-1-AP 1:1000) with K-562 cells lysate 3200ug.
Positive WB detected in K-562 cells
Positive IP detected in K-562 cells
Positive IHC detected in Human colon cancer tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:20-1:200
 ARID3A抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen ARID3A fusion protein ag5124 Full name AT rich interactive domain 3A (BRIGHT-like)
Calculated molecular
weight
63 kDa Observed molecular 
weight
75 kDa
GenBank accession 
number
BC060828 Gene ID (NCBI) 1820
Gene symbol ARID3A Synonyms ARID3A, BRIGHT, Dead ringer like protein 1, DRIL1, DRIL3, DRX, E2F binding protein 1, E2FBP1
Background ARID3A抗体

ARID3A is a nuclear matrix-associated transcription factor that stimulates immunoglobulin heavy chain (IgH) expression and Cyclin E1/E2F-dependent cell cycle progression. It activates IgH transcriptional initiation by binding to ATC-rich P sites within nuclear matrix attachment regions (MARs) flanking the IgH intronic enhancer (Emu) [PMID:17386101]. It is the founder of the 13-member (in humans) ARID (AT-Rich Interaction Domain) family, which share a highly conserved DNA binding domain, but function in diverse biological processes such as cell cycle regulated events, epigenetic post-translational modification, and chromatin remodeling [PMID:15927959,11959810,11283269]. ARID3A抗体

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