ALDH9A1,γ-氨基丁酸醛脱氢酶抗体

产品编号HZ-12461R
英文名称ALDH9A1
中文名称γ-氨基丁酸醛脱氢酶抗体
别 名4 trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; ALDH4; ALDH7; ALDH9; aldh9A1; E3; Gamma aminobutyraldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 神经生物学 信号转导 新陈代谢 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
ALDH9A1,γ-氨基丁酸醛脱氢酶抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量54kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ALDH9A1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ALDH9A1,γ-氨基丁酸醛脱氢酶抗体PubMedPubMed
产品介绍background:
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.

Function:
Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction.

Subunit:
Homotetramer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.

Post-translational modifications:
The N-terminus is blocked.

Similarity:
Belongs to the aldehyde dehydrogenase family.

Gene ID:
233

ALDH9A1,γ-氨基丁酸醛脱氢酶抗体Database links:
Entrez Gene: 223 Human
Entrez Gene: 56752 Mouse
Entrez Gene: 64040 Rat
Omim: 602733 Human
SwissProt: P49189 Human
SwissProt: Q9JLJ2 Mouse
SwissProt: Q9JLJ3 Rat
Unigene: 2533 Human
Unigene: 330055 Mouse
Unigene: 474999 Mouse
Unigene: 98155 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.