Tunicamycin (CAS: 11089-65-9)
产品名称: Tunicamycin (CAS: 11089-65-9)
英文名称: Tunicamycin
产品编号: SIH-397-5MG
产品价格: 0
产品产地: 加拿大
品牌商标: StressMarq
更新时间: null
使用范围: null
StressMarq
- 联系人 :
- 地址 : 加拿大
- 邮编 :
- 所在区域 : 其他
- 电话 : 138****6620; 点击查看
- 传真 : 点击查看
- 邮箱 : hedyl@stressmarq.com
As a nucleoside antibiotic, Tunicamycin blocks the formation of protein N-glycosidic linkages by inhibiting the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. This causes an induction of glucose-regulated protein 78 (GRP78) mRNA expression, which in turn increases ER stress and subsequently induces autophagy.