分子量:23.3 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human ICAM-2, His Tag by the LAL method.

Buffer:PBS, pH7.4

生物活性:

产品特性:Human ICAM-2, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 23.3 kDa. The predicted N-terminus is Ser 22. The reducing (R) protein migrates as 40-63 kDa in SDS-PAGE  due to glycosylation.

产品背景:Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 / CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.