BCAS1,乳腺癌相关蛋白1抗体

产品编号HZ-11462R
英文名称BCAS1
中文名称乳腺癌相关蛋白1抗体
别 名NABC1; AIBC 1; AIBC1; Amplified and overexpressed in breast cancer; BCAS 1; BCAS1; BCAS1_HUMAN; Breast carcinoma amplified sequence 1; Breast carcinoma-amplified sequence 1; Novel amplified in breast cancer 1.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
BCAS1,乳腺癌相关蛋白1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量62kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human BCAS1 (542-584aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
BCAS1,乳腺癌相关蛋白1抗体PubMedPubMed
产品介绍background:
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008]

Function:
Expressed in brain and prostate, and at lower levels in testis, intestine and colon. Overexpressed in most breast cancer cell lines and down-regulated in some colorectal tumors.

Subunit:
Homodimer. May interact with DYNLL1 and DYNLL2

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in brain and prostate, and at lowerlevels in testis, intestine and colon. Overexpressed in most breastcancer cell lines and down-regulated in some colorectal tumors.

BCAS1,乳腺癌相关蛋白1抗体Database links:
Entrez Gene: 8537 Human
Omim: 602968 Human
SwissProt: O75363 Human
Unigene: 728940 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.