MYL7,肌球蛋白轻链7抗体

产品编号HZ-9867R
英文名称MYL7
中文名称肌球蛋白轻链7抗体
别 名atrial isoform; MLC-2a; MLC2a; MLRA_HUMAN; MYL2A; MYL7; Mylc2a; Myosin light chain 2a; Myosin light chain 7 regulatory; Myosin light polypeptide 7 regulatory; Myosin regulatory light chain 2; Myosin regulatory light chain 2 atrial isoform; Myosin regulatory light chain 7.
说 明 书0.1ml 0.2ml
研究领域心血管 信号转导 细胞骨架 细胞外基质
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
MYL7,肌球蛋白轻链7抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量19kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human MYL7
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
MYL7,肌球蛋白轻链7抗体PubMedPubMed
产品介绍background:
Encoded by the MYL7 gene, myosin regulatory light chain 7, also designated Myosin regulatory light chain 2, atrial isoform (MLC-2a), is part of a hexameric complex of two heavy chains and four light chains predominantly expressed in adult atrial muscle. Myosin regulatory light chain 7 binds calcium and has been shown to be a useful molecular marker for cardiac chamber specification. The co-expression of myosin regulatory light chain 7 and myosin light chain 2 (MLC2v) in the outflow tract and atrioventricular canal, together with the single expression in the atrial (MYL7) and ventricular (MYL2) myo-cardium, permits the delineation of their boundaries. At the amino acid level there is 95% homology between the human and mouse myosin regulatory light chain 7 sequences.

Subunit:
Myosin is an hexamer of 2 heavy chains and 4 light chains.

Tissue Specificity:
Predominantly expressed in adult atrial muscle.

Similarity:
Contains 3 EF-hand domains.

Database links:
Entrez Gene: 58498 Human
Omim: 612147 Human
SwissProt: Q01449 Human
Unigene: 75636 Human

MYL7,肌球蛋白轻链7抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.