重组VEGF(血管内皮生长因子)

中文名称：重组VEGF(血管内皮生长因子)
英文名称：Recombinant Rabbit vegf
产品规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备而成(人类细胞)，目的蛋白包含序列() of Human vegf 在C端含有His标签。

vegf质量控制：＞95%(SEC-HPLC，还原性SDS-PAGE)


vegf制剂：冻干品

vegf保存：
冻干蛋白长期保存应置于-20℃以下，常温可稳定保存3周。
复溶蛋白溶液可在4℃保存2～7天。
复溶后的蛋白溶液应尽量避免反复冻融，可根据使用量分装冻存在-20℃以下长达3个月。

vegf复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
Dissolve the lyophilized protein in 1X PBS.
复溶后，请根据用量分装冻存，避免反复冻融。

关于vegf：
Vascular endothelial growth factor (VEGF) also known as vascular permeability factor (VPF) is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis. Two receptor tyrosine kinases have been described as putative VEGF receptors. Flt-1 (fms-like tyrosine kinase), and KDR (kinase-insert-domain-containing receptor) proteins have been shown to bind VEGF with high affinity. In vitro, VEGF is a potent endothelial cell mitogen. In cultured endothelial cells, VEGF can activate phospholipase C and induce rapid increases of free cytosolic Ca2+. VEGF has been shown to stimulate von Willebrand factor release from endothelial cells and induce expression of tissue factor activity in endothelial cells as well as in monocytes. VEGF has also been shown to be chemotactic for monocytes and osteoblasts. In vivo, VEGF can induce angiogenesis as well as increase microvascular permeability. As a vascular permeability factor, VEGF acts directly on the endothelium and does not degranulate mast cells. It promotes extravasation of plasma fibrinogen, leading to fibrin deposition which alters the tumor extracellular matrix. 

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！