FITC标记的磷酸化活化蛋白激酶D抗体
产品名称: FITC标记的磷酸化活化蛋白激酶D抗体
英文名称: Anti-phospho-JunD (Ser255)/FITC
产品编号: HZ-5466R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-phospho-JunD (Ser255)/FITC Conjugated antibody
FITC标记的磷酸化活化蛋白激酶D抗体
英文名称 | Anti-phospho-JunD (Ser255)/FITC |
中文名称 | FITC标记的磷酸化活化蛋白激酶D抗体 |
别 名 | JunD (phospho S255); JunD (Phospho Ser255); Transcription factor jun-D; jun D proto-oncogene; JUND1; AP-1; JUND; JUND1; MGC6245; MGC72300; AP 1; AP1; jun D proto oncogene; JunD FL isoform; JUND_HUMAN; Transcription factor jun D; transcription factor jun-D isoform JunD-FL; Jun-like transcription factor; pfam03957. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
产品类型 | 磷酸化抗体 |
研究领域 | 肿瘤 免疫学 信号转导 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Chicken, Dog, Cow, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 38kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human JunD around the phosphorylation site of Ser255 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'. Function: Transcription factor binding AP-1 sites. Subunit: Binds DNA as a dimer (By similarity). Interacts with MEN1; this interaction represses transcriptional activation. Subcellular Location: Nucleus. Similarity: Belongs to the bZIP family. Jun subfamily. Contains 1 bZIP (basic-leucine zipper) domain. Database links: Entrez Gene: 3727 Human Entrez Gene: 16478 Mouse Entrez Gene: 24518 Rat Omim: 165162 Human SwissProt: P17535 Human SwissProt: P15066 Mouse SwissProt: P52909 Rat Unigene: 2780 Human Unigene: 419851 Mouse Unigene: 46225 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Jun-D属于转录因子AP-1家族(Jun蛋白家族包括c-Jun、JunB和JunD |
原癌基因c-Jun was the first as the泡沫塑料identified禽类肉瘤病毒vjun of the同源基因。JunB和伊斯兰战士have been shown to be to their几乎identical cJun在C端区域,which are involved二聚化和DNA结合结构域的N端,他们whereas which are involved,在不同的转录活动。转录因子JunB is involved following the primary基因的活性在调节生长因子的反应。它binds to the DNA序列5' - [ 3 ](CG)。