LDLR polyclonal antibody-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
LDLR polyclonal antibody

LDLR polyclonal antibody

商家询价

产品名称： LDLR polyclonal antibody

英文名称： LDLR polyclonal antibody

产品编号： PAB8804

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152 点击查看
  • 传真 : 点击查看
  • 邮箱 : sales@abnova.com.tw
进入展台

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of LDLR.
  • Immunogen:
  • A synthetic peptide corresponding to residues surrounding amino acids 850 of human LDLR.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 160, 120, 50
  • Reactivity:
  • Bovine, Hamster, Human, Mouse, Rabbit, Rat
  • Specificity:
  • This antibody recognizes mature LDLR (160 KDa), LDLR precursor (120 KDa) and LDLR monomer (~50 KDa).
  • Form:
  • Liquid
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of LDLR expression in Jurkat cell (Lane 1) and NIH/3T3 (Lane 2) cell lysates.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3949
  • Gene Name:
  • LDLR
  • Gene Alias:
  • FH,FHC
  • Gene Description:
  • low density lipoprotein receptor
  • Gene Summary:
  • The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. [provided by RefSeq
  • Other Designations:
  • LDL receptor,low-density lipoprotein receptor class A domain-containing protein 3
  • Gene Pathway
  • Related Disease

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