DCLRE1C polyclonal antibody
产品名称： DCLRE1C polyclonal antibody
英文名称： DCLRE1C polyclonal antibody
产品编号： PAB18162
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of DCLRE1C.
- Immunogen:
- A synthetic peptide corresponding to human DCLRE1C.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- This antibody is specific to DCLRE1C.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya KNat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21.
- 2.
- A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans.
Li L, Moshous D, Zhou Y, Wang J, Xie G, Salido E, Hu D, de Villartay JP, Cowan MJ.J Immunol. 2002 Jun 15;168(12):6323-9.
- 3.
- Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.
Moshous D, Callebaut I, de Chasseval R, Corneo B, Cavazzana-Calvo M, Le Deist F, Tezcan I, Sanal O, Bertrand Y, Philippe N, Fischer A, de Villartay JP.Cell. 2001 Apr 20;105(2):177-86.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using DCLRE1C polyclonal antibody (Cat # PAB18162).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 64421
- Protein Accession#:
- Q96SD1
- Gene Name:
- DCLRE1C
- Gene Alias:
- A-SCID,DCLREC1C,FLJ11360,FLJ36438,RS-SCID,SCIDA,SNM1C
- Gene Description:
- DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq
- Other Designations:
- OTTHUMP00000019166,OTTHUMP00000019167,OTTHUMP00000019168,OTTHUMP00000019170,OTTHUMP00000019171,OTTHUMP00000019172,OTTHUMP00000019174,OTTHUMP00000045150,artemis protein,severe combined immunodeficiency, type a (Athabascan)
- Gene Pathway