YWHAG monoclonal antibody, clone J3H10
产品名称： YWHAG monoclonal antibody, clone J3H10
英文名称： YWHAG monoclonal antibody, clone J3H10
产品编号： MAB2048
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant YWHAG.
- Immunogen:
- Recombinant protein corresponding to amino acids 1-247 of human YWHAG.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG2b, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- 14-3-3gamma is upregulated by in vitro ischemia and binds to protein kinase Raf in primary cultures of astrocytes.
Chen XQ, Chen JG, Zhang Y, Hsiao WW, Yu AC.Glia. 2003 Jun;42(4):315-24.
- 2.
- The association of 14-3-3gamma and actin plays a role in cell division and apoptosis in astrocytes.
Chen XQ, Yu AC.Biochem Biophys Res Commun. 2002 Aug 23;296(3):657-63.
- Applications
- Western Blot
- The lysates of mouse brain (lane 1, 30 ug) and HeLa (lane 2, 30 ug) were resolved by SDS-PAGE and probed with YWHAG monoclonal antibody, clone J3H10 (Cat # MAB2048) (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 7532
- Protein Accession#:
- NP_036611
- Gene Name:
- YWHAG
- Gene Alias:
- 14-3-3GAMMA
- Gene Description:
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
- Omim ID:
- 605356
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq
- Other Designations:
- 14-3-3 gamma
- Gene Pathway