CCR5 polyclonal antibody
产品名称: CCR5 polyclonal antibody
英文名称: CCR5 polyclonal antibody
产品编号: PAB9833
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CCR5.
- Immunogen:
- A synthetic peptide corresponding to amino acids 6-20 of human CCR5.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.25-0.5 ug/lmL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Chemokine receptors: keys to AIDS pathogenesis?
Littman DR.Cell. 1998 May 29;93(5):677-80.
- 2.
- How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity.
Dimitrov DS.Cell. 1997 Dec 12;91(6):721-30.
- 3.
- Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.
Doranz BJ, Lu ZH, Rucker J, Zhang TY, Sharron M, Cen YH, Wang ZX, Guo HH, Du JG, Accavitti MA, Doms RW, Peiper SC.J Virol. 1997 Sep;71(9):6305-14.
- Entrez GeneID:
- 1234
- Gene Name:
- CCR5
- Gene Alias:
- CC-CKR-5,CCCKR5,CD195,CKR-5,CKR5,CMKBR5,IDDM22
- Gene Description:
- chemokine (C-C motif) receptor 5
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- C-C chemokine receptor 5,C-C chemokine receptor type 5,CCR5 chemokine receptor,chemokine (C-C) receptor 5,chemokine receptor CCR5,chemr13
- Related Disease
- Abnormalities, Multiple
- Abortion, Habitual
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Addison Disease
- Adenocarcinoma
- AIDS Dementia Complex
- AIDS-Related Opportunistic Infections
- Albuminuria
- Alzheimer Disease
- Alzheimer disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Aneurysm, Ruptured
- Aortic Aneurysm, Abdominal
- Aortic Valve Stenosis
- Arterial Occlusive Diseases
- Arthritis
- Arthritis, Juvenile Rheumatoid