LYN polyclonal antibody
产品名称： LYN polyclonal antibody
英文名称： LYN polyclonal antibody
产品编号： PAB18126
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LYN.
- Immunogen:
- A synthetic peptide corresponding to human LYN.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to LYN.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:300-1:1000)
Immunohistochemistry (1:50-1:100)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI.
Xiao W, Nishimoto H, Hong H, Kitaura J, Nunomura S, Maeda-Yamamoto M, Kawakami Y, Lowell CA, Ra C, Kawakami T.J Immunol. 2005 Nov 15;175(10):6885-92.
- 2.
- Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.
Contri A, Brunati AM, Trentin L, Cabrelle A, Miorin M, Cesaro L, Pinna LA, Zambello R, Semenzato G, Donella-Deana A.J Clin Invest. 2005 Feb;115(2):369-78.
- 3.
- A rapid translocation of CD45RO but not CD45RA to lipid rafts in IL-6-induced proliferation in myeloma.
Li FJ, Tsuyama N, Ishikawa H, Obata M, Abroun S, Liu S, Otsuyama K, Zheng X, Ma Z, Maki Y, Kawano MM.Blood. 2005 Apr 15;105(8):3295-302. Epub 2004 Dec 30.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from K-562 cells treated with H2O2 (100 uM, 30 mins), using LYN polyclonal antibody (Cat # PAB18126).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 4064
- Protein Accession#:
- P07948
- Gene Name:
- CD180
- Gene Alias:
- LY64,Ly78,MGC126233,MGC126234,RP105
- Gene Description:
- CD180 molecule
- Omim ID:
- 602226
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq
- Other Designations:
- CD180 antigen,lymphocyte antigen-64, radioprotective, 105kDa