SSX2 polyclonal antibody
产品名称： SSX2 polyclonal antibody
英文名称： SSX2 polyclonal antibody
产品编号： PAB12322
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SSX2.
- Immunogen:
- A synthetic peptide corresponding to amino acids at C-terminus of human SSX2.
- Sequence:
- NREAQEKEERRGTAHRWSSQNTHNIGRF
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- Identical to the related rat and mouse sequence.
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Storage Buffer:
- Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.
Crew AJ, Clark J, Fisher C, Gill S, Grimer R, Chand A, Shipley J, Gusterson BA, Cooper CS.EMBO J. 1995 May 15;14(10):2333-40.
- Entrez GeneID:
- 6757
- Gene Name:
- SSX2
- Gene Alias:
- HD21,HOM-MEL-40,MGC119055,MGC15364,MGC3884,SSX
- Gene Description:
- synovial sarcoma, X breakpoint 2
- Omim ID:
- 300192
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000024290,OTTHUMP00000024291,sarcoma, synovial, X-chromosome-related 2,synovial sarcoma, X breakpoint 2, isoform b,synovial sarcoma, X breakpoint 2B