Wortmannin (CAS: 19545-26-7)
产品名称: Wortmannin (CAS: 19545-26-7)
英文名称: Wortmannin
产品编号: SIH-392-5MG
产品价格: 0
产品产地: 加拿大
品牌商标: StressMarq
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Wortmannin is a steroid metabolite from the fungi Penicillium funiculosum. It specifically and irreversibly inhibits phosphatidylinositol 3-kinase (PI3-K). This in turn has been shown to inhibit the metabolic effects of insulin, yet the insulin receptor kinase activity is not altered. Because PI3-K is involved in membrane trafficking, and membrane trafficking is important in autophagy, Wortmannin also inhibits autophagy.