Wortmannin (CAS: 19545-26-7)-常用生化试剂-试剂-生物在线
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Wortmannin (CAS: 19545-26-7)

Wortmannin (CAS: 19545-26-7)

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产品名称: Wortmannin (CAS: 19545-26-7)

英文名称: Wortmannin

产品编号: SIH-392-5MG

产品价格: 0

产品产地: 加拿大

品牌商标: StressMarq

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Wortmannin is a steroid metabolite from the fungi Penicillium funiculosum. It specifically and irreversibly inhibits phosphatidylinositol 3-kinase (PI3-K).  This in turn has been shown to inhibit the metabolic effects of insulin, yet the insulin receptor kinase activity is not altered. Because PI3-K is involved in membrane trafficking, and membrane trafficking is important in autophagy, Wortmannin also inhibits autophagy.