FITC标记的锌指蛋白ZBTB6抗体
产品名称： FITC标记的锌指蛋白ZBTB6抗体
英文名称： Anti-ZBTB6/FITC
产品编号： HZ-13582R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZBTB6/FITC Conjugated antibody
FITC标记的锌指蛋白ZBTB6抗体
| 英文名称 | Anti-ZBTB6/FITC |
| 中文名称 | FITC标记的锌指蛋白ZBTB6抗体 |
| 别 名 | ZBTB 6; ZBTB6; ZBTB6_HUMAN; ZID; Zinc finger and BTB domain containing protein 6; Zinc finger and BTB domain-containing protein 6; Zinc finger protein 482; Zinc finger protein with interaction domain; ZNF 482; ZNF482. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 转录调节因子 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 48kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZBTB6/ZNF482 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed with highest levels in brain. Similarity: Contains 1 BTB (POZ) domain. Contains 4 C2H2-type zinc fingers. Database links: Entrez Gene: 10773 Human Entrez Gene: 241322 Mouse Entrez Gene: 366029 Rat Entrez Gene: 417108 Chicken Entrez Gene: 540218 Cow Omim: 605976 Human SwissProt: Q0V8G8 Cow SwissProt: Q15916 Human SwissProt: Q8K088 Mouse Unigene: 654596 Human Unigene: 330182 Mouse Unigene: 39069 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
锌指蛋白含有DNA结合结构域，具有多种功能，其中大多数包含某种形式的转录激活或抑制。大多数锌指蛋白包含Krüppel型DNA结合域和KRAB域，它们被认为与KAP1相互作用，从而募集组蛋白修饰蛋白。锌指和BTB结构域蛋白5(ZBTB5)是Krüppel C2H2型锌指蛋白家族的677个氨基酸成员。ZBTB5定位于细胞核，含有BTB结构域，也称为POZ结构域，抑制DNA结合，介导同型和异型二聚化。BTB结构域的特征提示ZBTB5具有转录调节功能。