FITC标记的核通道蛋白SEH1L抗体
产品名称： FITC标记的核通道蛋白SEH1L抗体
英文名称： Anti-SEH1L/FITC
产品编号： HZ-8721R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SEH1L/FITC Conjugated antibody
FITC标记的核通道蛋白SEH1L抗体
| 英文名称 | Anti-SEH1L/FITC |
| 中文名称 | FITC标记的核通道蛋白SEH1L抗体 |
| 别 名 | Nucleoporin SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like protein; SEC13L; Seh 1; SEH1-like (S. cerevisiae); SEH1_HUMAN; SEH1A; SEH1B; SEH1L |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 染色质和核信号 信号转导 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SEH1L |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Seh1 is a 421 amino acid protein belonging to the WD repeat Sec13 family. Localized to the nucleus, Seh1 is a component of the nuclear pore complex Nup107-160. Nuclear pore complexes control bidirectional transport of macromolecules between the cytoplasm and the nucleus. All components of the complex Nup107-160, including Seh1, localize to the kinetochores during mitosis. Seh1 is expressed as two isoforms produced by alternative splicing and contains six WD repeats. Function: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Subcellular Location: Chromosome; centromere; kinetochore. Nucleus; nuclear pore complex. Similarity: Belongs to the WD repeat SEC13 family. Contains 6 WD repeats. Database links: Entrez Gene: 81929 Human Omim: 609263 Human SwissProt: Q96EE3 Human Unigene: 301048 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SEH1是属于WD重复SEC13家族的421氨基酸蛋白。定位于细胞核，SEH1是核孔复合物NUP107—160的一个组成部分。核孔复合物控制大分子在细胞质和细胞核之间的双向转运。复杂的NUP107—160的所有成分，包括SEH1，定位于有丝分裂过程中的着丝粒。SEH1表达为两个异构体产生的选择性剪接，并包含六个WD重复。