TRIM35,TRIM35蛋白抗体

产品编号HZ-9149R
英文名称TRIM35
中文名称TRIM35蛋白抗体
别 名Hemopoietic lineage switch protein 5; HLS5; KIAA1098; Macrophage derived apoptosis inducing RBCC protein; MAIR; NC8; Protein MAIR; Protein Nc8; Tripartite motif containing 35; Tripartite motif containing protein 35; TRI35_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
TRIM35,TRIM35蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量57kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human TRIM35
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
TRIM35,TRIM35蛋白抗体PubMedPubMed
产品介绍background:
TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2 and a coiled-coil region. TRIM35 may play a role as a tumor suppressor and is implicated in the cell death mechanism. There are two named isoforms.

Function:
May play a role as a tumor suppressor. Implicated in the cell death mechanism (By similarity).

Subcellular Location:
Cytoplasm. Nucleus. Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.

TRIM35,TRIM35蛋白抗体Similarity:
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Gene ID:
23087

Database links:
Entrez Gene: 23087 Human
Entrez Gene: 66854 Mouse
Entrez Gene: 498538 Rat
SwissProt: Q9UPQ4 Human
SwissProt: Q8C006 Mouse
SwissProt: Q5RKG6 Rat
Unigene: 104223 Human
Unigene: 43871 Mouse
Unigene: 153980 Rat

TRIM35,TRIM35蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.