EGFR Rabbit pAb (APR18422N)
产品名称: EGFR Rabbit pAb (APR18422N)
英文名称: EGFR Rabbit pAb (APR18422N)
产品编号: APR18422N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: WB (H1975, Zika virus, Mus musculus, Homo sapiens) IHC (Human glioma, Mus musculus, Homo sapiens) IF (Homo sapiens)
分子量:Calculated MW: 44kDa/69kDa/77kDa/134kDa Observed MW: 175KDa 细胞定位:Cell membrane, Endoplasmic reticulum membrane, Endosome, Endosome membrane, Golgi apparatus membrane, Nucleus membrane, Nucleus, Secreted, Single-pass type I membrane protein 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:100 总结:The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.