Encephalopsin,感光视觉蛋白ECPN抗体

产品编号HZ-14590R
英文名称Encephalopsin
中文名称感光视觉蛋白ECPN抗体
别 名ECPN; Encephalopsin; ERO; NMO 1; NMO1; OPN 3; OPN3; OPN3_HUMAN; Opsin 3; Opsin-3; Opsin3; Panopsin.
说 明 书0.1ml 0.2ml
研究领域神经生物学 G蛋白偶联受体 G蛋白信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit,
Encephalopsin,感光视觉蛋白ECPN抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Encephalopsin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Encephalopsin,感光视觉蛋白ECPN抗体PubMedPubMed
产品介绍background:
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008]

Function:
May play a role in encephalic photoreception.

Subcellular Location:
Membrane.

Tissue Specificity:
Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Opsin subfam

Gene ID:
23596

Encephalopsin,感光视觉蛋白ECPN抗体Database links:
Entrez Gene: 23596 Human
Entrez Gene: 13603 Mouse
Omim: 606695 Human
SwissProt: Q9H1Y3 Human
SwissProt: Q9WUK7 Mouse
Unigene: 409081 Human
Unigene: 32744 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.