FITC标记的胶原蛋白9抗体
产品名称： FITC标记的胶原蛋白9抗体
英文名称： Anti-Collagen IX/FITC
产品编号： HZ-13962R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Collagen IX/FITC Conjugated antibody
FITC标记的胶原蛋白9抗体
| 中文名称 | FITC标记的胶原蛋白9抗体 |
| 别 名 | Collagen alpha 1(IX) chain; Collagen type IX alpha 1; EDM6; MED; STL4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 89kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Collagen IX |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Type IX collagen proteoglycan is a major component of hyaline cartilages where it is located on the surface of the collagen fibrils so that a collagenous domain of the molecule (called COL 3) and a non-collagenous domain (called NC4) project at periodic distances away from the surface of the fibrils. Function: Structural component of hyaline cartilage and vitreous of the eye. Subunit: Heterotrimer of an alpha 1(IX), an alpha 2(IX) and an alpha 3(IX) chain. Subcellular Location: Secreted, extracellular space, extracellular matrix (By similarity). Tissue Specificity: Cytoplasmic Post-translational modifications: Covalently linked to the telopeptides of type II collagen by lysine-derived cross-links. Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. DISEASE: Multiple epiphyseal dysplasia 6 (EDM6) [MIM:614135]: A generalized skeletal dysplasia associated with significant morbidity. Joint pain, joint deformity, waddling gait, and short stature are the main clinical signs and symptoms. Radiological examination of the skeleton shows delayed, irregular mineralization of the epiphyseal ossification centers and of the centers of the carpal and tarsal bones. Multiple epiphyseal dysplasia is broadly categorized into the more severe Fairbank and the milder Ribbing types. The Fairbank type is characterized by shortness of stature, short and stubby fingers, small epiphyses in several joints, including the knee, ankle, hand, and hip. The Ribbing type is confined predominantly to the hip joints and is characterized by hands that are normal and stature that is normal or near-normal. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. Contains 10 collagen-like domains. Contains 1 laminin G-like domain. Database links: Entrez Gene: 1297 Human Entrez Gene: 12839 Mouse Entrez Gene: 305104 Rat Omim: 120210 Human SwissProt: P20849 Human SwissProt: Q05722 Mouse SwissProt: P20850 Rat Unigene: 590892 Human Unigene: 154662 Mouse Unigene: 90726 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
IX型胶原蛋白聚糖是透明软骨的主要成分，它位于胶原原纤维的表面，使得分子的胶原结构域（称为COL 3）和非胶原结构域（称为NC4）在远离原纤维表面的周期性距离处突出。S.