TERF1 polyclonal antibody
产品名称： TERF1 polyclonal antibody
英文名称： TERF1 polyclonal antibody
产品编号： PAB2607
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TERF1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human TERF1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation.
Kim MK, Kang MR, Nam HW, Bae YS, Kim YS, Chung IK.J Biol Chem. 2008 May 16;283(20):14144-52. Epub 2008 Mar 17.
- 2.
- Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation.
Etheridge KT, Compton SA, Barrientos KS, Ozgur S, Griffith JD, Counter CM.J Biol Chem. 2008 Mar 14;283(11):6935-41. Epub 2008 Jan 3.
- 3.
- Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.
Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H.Exp Cell Res. 2008 Mar 10;314(5):1115-24. Epub 2007 Dec 14.
- Entrez GeneID:
- 7013
- Gene Name:
- TERF1
- Gene Alias:
- FLJ41416,PIN2,TRBF1,TRF,TRF1,hTRF1-AS,t-TRF1
- Gene Description:
- telomeric repeat binding factor (NIMA-interacting) 1
- Omim ID:
- 600951
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq
- Other Designations:
- telomeric repeat binding factor 1,telomeric repeat binding protein 1