Amphiphysin抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Amphiphysin抗体

Amphiphysin抗体

商家询价

产品名称： Amphiphysin抗体

英文名称： AmphiphysinAntibody

产品编号： XY13379-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 AMPHIPHYSIN抗体

Applications
In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Published applications IF, IHC, WB Publications 6 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Mouse
Images
Prev12NextView more validation data
  • 13379-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 13379-1-AP(AMPH antibody) at dilution of 1:1500
  • 13379-1-AP;human pancreas cancerImmunohistochemical of paraffin-embedded human pancreas cancer using 13379-1-AP(AMPH antibody) at dilution of 1:100 (under 10x lens)
  • 13379-1-AP;human pancreas cancerImmunohistochemical of paraffin-embedded human pancreas cancer using 13379-1-AP(AMPH antibody) at dilution of 1:100 (under 40x lens)
  • 13379-1-AP;mouse brain tissueIP Result of anti-AMPH (IP:13379-1-AP, 4ug; Detection:13379-1-AP 1:1500) with mouse brain tissue lysate 4000ug.
Positive WB detected in Mouse brain tissue, mouse lung tissue
Positive IP detected in Mouse brain tissue
Positive IHC detected in Human pancreas cancer tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
 AMPHIPHYSIN抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information AMPHIPHYSIN抗体
Immunogen Amphiphysin fusion protein ag4204 Full name Amphiphysin
Calculated molecular
weight		 695aa,76 kDa Observed molecular 
weight		 115-125 kDa
GenBank accession 
number		 BC034376 Gene ID (NCBI) 273
Gene symbol AMPH Synonyms AMPH, AMPH1, Amphiphysin
Background

Amphiphysin (AMPH), a synaptic vesicle-associated protein that is highly concentrated in nerve terminal, is an autoantigen of Stiff-Man syndrome with breast cancer. Amphiphysin contains a N-terminal BAR (Bin1/Amphiphysin/Rv167) domain followed by an endocytosis domain, and a C-terminal SH3 domain. Amphiphysin has been proposed to function as a linker between the clathrin coat and dynamin in the endocytosis of synaptic vesicles. It may also participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. (PMID: 8552632; 8245793; 10559861) AMPHIPHYSIN抗体

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