Recombinant Human sCD27 Ligand
产品名称： Recombinant Human sCD27 Ligand
英文名称： Recombinant Human sCD27 Ligand
产品编号： 310-30
产品价格： 0
产品产地： USA
品牌商标： PEPROTECH
更新时间： null
使用范围： null
上海研卉生物科技有限公司
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产品编号:
310-30
别名:
TNFSF7, CD70
描述:
CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. PeproTech’s recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.
氨基酸序列:
HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P
来源:
CHO cells
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors.