DPEP1,脱氢肽酶1抗体

产品编号HZ-14414R
英文名称DPEP1
中文名称脱氢肽酶1抗体
别 名Dehydropeptidase-I; Dipeptidase 1 (renal); Dipeptidase 1; DPEP1; DPEP1_HUMAN; hRDP; MBD1; MDP; Microsomal dipeptidase; RDP; Renal dipeptidase.
说 明 书0.1ml 0.2ml
研究领域肿瘤 心血管 细胞生物 神经生物学 泛素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,
DPEP1,脱氢肽酶1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量44kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DPEP1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DPEP1,脱氢肽酶1抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.

Subcellular Location:
Apical cell membrane. Cell projection; microvillus membrane. Brush border membrane.

Similarity:
Belongs to the peptidase M19 family.

Gene ID:
1800

Database links:
Entrez Gene: 1800 Human
Omim: 179780 Human
SwissProt: P16444 Human
Unigene: 109 Human

DPEP1,脱氢肽酶1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.