分子量:32.9 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human Secretagogin, His Tag by the LAL method.

Buffer:50 mM Tris, 150 mM NaCl, pH 7.5

生物活性:

产品特性:Human Secretagogin, His Tag is fused with a polyhistidine tag at the N-terminus, and has a calculated MW of 32.9 kDa. The predicted N-terminus is Met. The reducing (R) protein migrates as 33 kDa in SDS-PAGE .

产品背景:Secretagogin (SCGN) is also known as SECRET, which is a secreted calcium-binding protein found in the cytoplasm. SCGN is related to calbindin D-28K and calretinin. Also, SCGN is thought to be involved in potassium chloride-stimulated calcium flux and cell proliferation and plays an important role in the release of the stress hormone Corticotropin-releasing hormone (CRH) and which only then enables stress processes in the brain. As for sequence similarities, SCGN contains 6 EF-hand domains.