Active人IGF1全长蛋白质-蛋白质/抗原/多肽-试剂-生物在线

产品名称： Active人IGF1全长蛋白质

英文名称： IBP1 IGF I IGF IA IGF IB IGF-I Igf1 IGF1_HUMAN IGFI IGFIA Insulin like growth factor 1 Insulin like growth factor 1 (somatomedin C) Insulin

产品编号： ab9573

产品价格： 0

产品产地：英国

品牌商标： abcam

更新时间： null

使用范围： null

深圳市宇德立生物科技有限公司

进入展台

Our Abpromise guarantee covers the use of ab9573 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用
Functional Studies

SDS-PAGE
内毒素水平< 0.100 Eu/µg
形式Lyophilised
补充说明The biological activity is determined by its ability to stimulate the proliferation of mouse FDC-P1 cells. The ED₅₀ was determined by a cell proliferation assay using FDC-P1 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg. Reconstitute in water.
浓度由溶解方法决定由溶解方法决定

稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

n/a

This product is an active protein and may elicit a biological response in vivo, handle with caution.
复溶Reconstitute with 100 ul of deionised water (or equivalent Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.

别名
- IBP1
- IGF I
- IGF IA
see all
功能The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
疾病相关Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
序列相似性Belongs to the insulin family.
细胞定位Secreted.