Cyclin T1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Cyclin T1 抗体

Cyclin T1 抗体

商家询价

产品名称： Cyclin T1 抗体

英文名称： Cyclin T1 Antibody

产品编号： XY20992-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 CYCLIN T1 抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Published applications WB Publications 1 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev1NextView more validation data
  • 20992-1-AP;K-562 cellK-562 cells were subjected to SDS PAGE followed by western blot with 20992-1-AP(CCNT1 antibody) at dilution of 1:300
Positive WB detected in K-562 cells, A431 cells, HeLa cells, Jurkat cells, Y79 cells
Recommended dilution WB : 1:200-1:1000
 CYCLIN T1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Peptide Full name Cyclin T1
Calculated molecular
weight		 81 kDa Observed molecular 
weight		 87 kDa
GenBank accession 
number		 NM_001240 Gene ID (NCBI) 904
Gene symbol CCNT1 Synonyms CCNT, CCNT1, Cyclin T, cyclin T1, CYCT1, HIVE1
Background CYCLIN T1 抗体

CCNT1, also named as CycT1, belongs to the cyclin family and Cyclin C subfamily. It is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex which also called positive transcription elongation factor B (P-TEFb). In case of HIV or SIV infections, CCNT1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). CCNT1 serves as an essential cofactor for Tat, by promoting RNA Pol II activation,  CYCLIN T1 抗体

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