PCNA monoclonal antibody (M04), clone S1
产品名称： PCNA monoclonal antibody (M04), clone S1
英文名称： PCNA monoclonal antibody (M04), clone S1
产品编号： H00005111-M04
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant PCNA.
- Immunogen:
- PCNA (AAH00491, 1 a.a. ~ 261 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (54.45 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- PCNA monoclonal antibody (M04), clone S1. Western Blot analysis of PCNA expression in PC-12 ( Cat # L012V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- PCNA monoclonal antibody (M04), clone S1 Western Blot analysis of PCNA expression in Hela NE ( Cat # L013V3 ).
- Protocol Download
- Western Blot (Cell lysate)
- PCNA monoclonal antibody (M04), clone S1. Western Blot analysis of PCNA expression in Raw 264.7 ( Cat # L024V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- PCNA monoclonal antibody (M04), clone S1. Western Blot analysis of PCNA expression in NIH/3T3 ( Cat # L018V1 ).
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of PCNA expression in transfected 293T cell line by PCNA monoclonal antibody (M04), clone S1.
Lane 1: PCNA transfected lysate(28.8 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PCNA is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 5111
- GeneBank Accession#:
- BC000491
- Protein Accession#:
- AAH00491
- Gene Name:
- PCNA
- Gene Alias:
- MGC8367
- Gene Description:
- proliferating cell nuclear antigen
- Omim ID:
- 176740
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
- Other Designations:
- DNA polymerase delta auxiliary protein,OTTHUMP00000030189,OTTHUMP00000030190,cyclin
- Interactome
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Colorectal Neoplasms
- Disease Progression
- DNA Damage
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Glioma
- Graft vs Host Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Laryngeal Neoplasms
- Lung Neoplasms
- Meningeal Neoplasms
- Meningioma