CDH1 polyclonal antibody
产品名称： CDH1 polyclonal antibody
英文名称： CDH1 polyclonal antibody
产品编号： PAB11203
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against partial recombinant CDH1.
- Immunogen:
- Recombinant protein corresponding to amino acids 600-707 of human CDH1.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 120
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- Lot specific
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:30)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 999
- Gene Name:
- CDH1
- Gene Alias:
- Arc-1,CD324,CDHE,ECAD,LCAM,UVO
- Gene Description:
- cadherin 1, type 1, E-cadherin (epithelial)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq
- Other Designations:
- cadherin 1, E-cadherin (epithelial),cadherin 1, type 1,calcium-dependent adhesion protein, epithelial,cell-CAM 120/80,uvomorulin
- Related Disease
- Adenocarcinoma
- Asthma
- Asthma
- Breast cancer
- Breast Neoplasms
- Bronchiolitis, Viral
- Carcinoma
- Carcinoma, Ductal, Breast
- Carcinoma, Hepatocellular
- Carcinoma, Large Cell
- Carcinoma, Lobular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cleft Lip
- Cleft Palate
- Colitis, Ulcerative
- Colorectal Neoplasms