Anti-SDHB Polyclonal Antibody
产品名称: Anti-SDHB Polyclonal Antibody
英文名称: CWS2;IP;PGL4;SDH;SDH1;SDH2;SDHIP
产品编号: K002093P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB
北京索莱宝科技有限公司--实验室产品
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Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.