CHI3L1,软骨糖蛋白39抗体

产品编号HZ-10215R
英文名称CHI3L1
中文名称软骨糖蛋白39抗体
别 名CHI3L1; 39 kDa synovial protein; ASRT7; Cartilage glycoprotein 39; CGP39; chitinase 3 like 1 (cartilage glycoprotein 39); chitinase 3 like 1; Chitinase 3 like protein 1 precursor; chitinase; GP 39; GP39; HC gp39; HCGP 3P; HCgp39; YKL 40; YKL40; CGP-39; CH3L1_HUMAN; chitinase 3 like 1; Chitinase-3-like protein 1 hCGP-39; YKL-40; YYL 40.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
CHI3L1,软骨糖蛋白39抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
细胞定位细胞外基质 分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CHI3L1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CHI3L1,软骨糖蛋白39抗体PubMedPubMed
产品介绍background:
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009]

Function:
Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.

Subunit:
Monomer.

Subcellular Location:
Secreted, extracellular space.

Tissue Specificity:
Present in articular chondrocytes, synovial cells as well as in liver. Undetectable in muscle tissues, lung, pancreas, mononuclear cells, or fibroblasts.

Similarity:
Belongs to the glycosyl hydrolase 18 family.

Gene ID:
1116

Database links:
Entrez Gene: 1116 Human
Entrez Gene: 12654 Mouse
Entrez Gene: 396865 Pig
Entrez Gene: 89824 Rat
Omim: 601525 Human
SwissProt: P36222 Human
SwissProt: Q61362 Mouse
SwissProt: Q5RBP6 Orangutan
SwissProt: Q29411 Pig
SwissProt: Q9WTV1 Rat
Unigene: 382202 Human
Unigene: 38274 Mouse
Unigene: 68940 Rat

CHI3L1,软骨糖蛋白39抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.