Anti-Pannexin 1抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-Pannexin 1抗体

Anti-Pannexin 1抗体

商家询价

产品名称: Anti-Pannexin 1抗体

英文名称: Pannexin 1

产品编号: YB--21015R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Pannexin 1抗体

产品编号 YB-21015R
英文名称 Pannexin 1
中文名称 间隙连接蛋白PANX1抗体
别    名 innexin; MRS1; Pannexin 1; Pannexin-1; Panx1; PANX1_HUMAN; PX1; UNQ2529.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  神经生物学  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Pannexin 1:61-106/426 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008]

Function:
Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.

Subunit:
Homohexamer. Forms homomeric or PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes (By similarity). 

Subcellular Location:
Cell membrane. Cell junction > gap junction. Endoplasmic reticulum membrane.

Similarity:
Belongs to the pannexin family.

SWISS:
Q96RD7

Gene ID:
24145

Database links:

Entrez Gene: 24145 Human

Entrez Gene: 55991 Mouse

Entrez Gene: 100171730 Orangutan

Entrez Gene: 315435 Rat

Omim: 608420 Human

SwissProt: Q96RD7 Human

SwissProt: Q9JIP4 Mouse

SwissProt: Q5REE3 Orangutan

SwissProt: P60570 Rat

Unigene: 591976 Human

Unigene: 142253 Mouse

Unigene: 204521 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Sample:Muscle (Mouse)Lysate at 40 ug
Primary: Anti-Pannexin 1(bs-21015R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 48kD
Observed band size: 53kD