FITC标记的平滑肌样蛋白1抗
产品名称： FITC标记的平滑肌样蛋白1抗
英文名称： Anti-SMTNL1/FITC
产品编号： HZ-12644R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SMTNL1/FITC Conjugated antibody
FITC标记的平滑肌样蛋白1抗
| 英文名称 | Anti-SMTNL1/FITC |
| 中文名称 | FITC标记的平滑肌样蛋白1抗 |
| 别 名 | Calponin homology associated smooth muscle protein; CHASM; OTTHUMP00000235021; Smoothelin like 1; Smoothelin like protein 1; SMTNL1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转录调节因子 细胞骨架 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SMTNL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: SMTNL1, which is a member of the smoothelin (SMTN; MIM 602127) family, regulates contraction and relaxation of skeletal and smooth muscle fibers and mediates vascular adaptation to exercise (Wooldridge et al., 2008 [PubMed 18310078]).[supplied by OMIM, Dec 2010] Function: Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). Subcellular Location: Cytoplasm ?myofibril. Cytoplasm ?myofibril ?sarcomere ?I band By similarity. Cytoplasm ?myofibril ?sarcomere ?M line. Nucleus. Note: Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm. Phosphorylation at Ser-301 promotes translocation to the nucleus, Tissue Specificity: Expressed in striated muscles, specifically in type 2a fibers (at protein level). Post-translational modifications: Maximal phosphorylation of Ser-299 correlates with maximal relaxation of aorta in response to acetylcholine. Similarity: Belongs to the smoothelin family. Contains 1 CH (calponin-homology) domain. Database links: Entrez Gene: 219537 Human Omim: 613664 Human SwissProt: A8MU46 Human Unigene: 68756 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SMTNL1是平滑肌蛋白(SMTN；MIM 602127)家族的成员，调节骨骼肌纤维和平滑肌纤维的收缩和松弛，并介导血管对运动的适应(Wooldridge等人，2008[PubMed 18310078])。