PARK2 (Human) Recombinant Protein (Q01)
产品名称: PARK2 (Human) Recombinant Protein (Q01)
英文名称: PARK2 (Human) Recombinant Protein (Q01)
产品编号: H00005071-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PARK2 partial ORF ( AAH22014, 288 a.a. - 387 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- PCVGTGDTVVLRGALGGFRRGVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGYGQRRTK
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5071
- GeneBank Accession#:
- BC022014
- Protein Accession#:
- AAH22014
- Gene Name:
- PARK2
- Gene Alias:
- AR-JP,LPRS2,PDJ,PRKN
- Gene Description:
- Parkinson disease (autosomal recessive, juvenile) 2, parkin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq
- Other Designations:
- E3 ubiquitin ligase,OTTHUMP00000017565,OTTHUMP00000017566,OTTHUMP00000017567,parkin,parkin 2
- Interactome
- Gene Pathway
- Related Disease
- Alzheimer disease
- Cardiovascular Diseases
- Choice Behavior
- Cognition Disorders
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Disease Progression
- Disease Susceptibility
- Dystonic Disorders
- Edema
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease
- Leprosy
- Movement Disorders
- Nerve Degeneration
- Neuropsychological Tests
- Paratyphoid Fever
- Parkinson Disease