人促血小板生成素重组蛋白是在大肠杆菌中重组表达的，是一条单链、非糖基化的多肽链，包含有174个氨基酸，分子量为18608Da，其中就包含了Mp1-配体蛋白的受体结合域。

Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes，the bone marrow cells that fragment into large numbers of platelets

TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

HumanZyme始建于2005年。世界上首家从人细胞生产人类逼真蛋白的知名公司。产品包括：人源化的细胞因子、及相关的抗体、人源化的重组白蛋白、和树突细胞培养试剂盒。产品行销到世界各地，产品受到广泛的好评。HumanZyme利用自己的专利技术，突破了人细胞宿主表达人类蛋白低的瓶颈，研制成了既能贴壁生长又能悬浮培养的细胞系。这不仅可以供应实验室规模量，而且可以大规模GMP生产，以满足临床前和临床需求。HumanZyme 是独家可以提供无动物源污染 和无异源蛋白污染 的公司。