分子量:37.5 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Influenza A [A/Shanghai/2/2013(H7N9)] HA1 by the LAL method.

Buffer:PBS, pH7.4

生物活性:

产品特性:Influenza A [A/Shanghai/2/2013(H7N9)] HA1 is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 37.5 kDa. The predicted N-terminus is Asp 19. The reducing (R) protein migrates as 43-50 kDa in SDS-PAGE .

产品背景:Influenza, commonly known as "the flu", is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus). H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.