LRRK2 polyclonal antibody
产品名称： LRRK2 polyclonal antibody
英文名称： LRRK2 polyclonal antibody
产品编号： PAB2629
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LRRK2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to residues surrounding L893 of human LRRK2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Dynamic and redundant regulation of LRRK2 and LRRK1 expression.
Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB.BMC Neurosci. 2007 Nov 28;8:102.
- Application Image
- Immunohistochemistry
- ELISA
- Entrez GeneID:
- 120892
- Protein Accession#:
- XP_058513
- Gene Name:
- LRRK2
- Gene Alias:
- AURA17,DARDARIN,PARK8,RIPK7,ROCO2
- Gene Description:
- leucine-rich repeat kinase 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq
- Other Designations:
- Parkinson disease (autosomal dominant) 8,augmented in rheumatoid arthritis 17
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aphasia, Primary Progressive
- Chromosome Aberrations
- Cognition
- Cognition Disorders
- Crohn Disease
- Dementia
- Disease Progression
- Dominance, Cerebral
- Dyskinesias
- Dystonic Disorders
- Essential Tremor
- Essential tremor
- Functional Laterality
- Gaucher disease
- Genetic Predisposition to Disease
- Heredodegenerative Disorders, Nervous System
- Huntington Disease