MSH2 monoclonal antibody, clone 1B3=3A2B8C
产品名称： MSH2 monoclonal antibody, clone 1B3=3A2B8C
英文名称： MSH2 monoclonal antibody, clone 1B3=3A2B8C
产品编号： MAB10812
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant MSH2.
- Immunogen:
- Recombinant protein corresponding to human MSH2.
- Host:
- Mouse
- Reactivity:
- Human, Monkey
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using MSH2 monoclonal antibody, clone 1B3=3A2B8C (Cat # MAB10812) against HeLa (1), A-549 (2), A-431 (3) and HEK293 (4) cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human breast cancer (A) and lung cancer (B) tissues, showing nuclear localization using MSH2 monoclonal antibody, clone 3A2B8C (Cat # MAB10812) with DAB staining.
- Entrez GeneID:
- 4436
- Gene Name:
- MSH2
- Gene Alias:
- COCA1,FCC1,HNPCC,HNPCC1,LCFS2
- Gene Description:
- mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq
- Other Designations:
- mutS homolog 2
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyposis Coli
- Anticipation, Genetic
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Papillary
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Cell Transformation, Neoplastic
- Chromosomal Instability
- Chromosome Deletion
- Chronic Disease
- Colon cancer