CRLF3,细胞因子受体样因子3抗体

产品编号HZ-14062R
英文名称CRLF3
中文名称细胞因子受体样因子3抗体
别 名CREME 9; CREME9; CRLF 3; CRLM9; Cytokine receptor like factor 3; Cytokine receptor like molecule 9; Cytokine receptor related protein 4; CYTOR4; FRWS; MGC20661; P48; p48.2; Type I cytokine receptor like factor; Type I cytokine receptor like factor p48; CRLF3_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 神经生物学 细胞周期蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Cow, Rabbit,
CRLF3,细胞因子受体样因子3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量50kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CRLF3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CRLF3,细胞因子受体样因子3抗体PubMedPubMed
产品介绍background:
This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012]

Function:
CRLF3 (Cytokine receptor-like factor 3) contains one fibronectin type-III domain. It is expressed in skin and squamous cell carcinoma (SCC) and in lesion actinic keratosis (AK).

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK).

Similarity:
Belongs to the cytokine receptor-like factor 3 family.
Contains 1 fibronectin type-III domain.

Gene ID:
51379

Database links:
Entrez Gene: 51379 Human
Entrez Gene: 54394 Mouse
Omim: 614853 Human
SwissProt: Q8IUI8 Human
SwissProt: Q9Z2L7 Mouse
Unigene: 649372 Human
Unigene: 272093 Mouse

CRLF3,细胞因子受体样因子3抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.