NFYA polyclonal antibody
产品名称: NFYA polyclonal antibody
英文名称: NFYA polyclonal antibody
产品编号: PAB11297
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NFYA.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NFYA.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- CHO-7 cells were cultured in the absence (I) or presence (S) of cholesterol.
Equivalent aliquots of chromatin from each sample containing ~50 ug of total protein were subjected to analysis by SDS-PAGE and immunoblot.
Using NFYA polyclonal antibody (Cat # PAB11297) at a 1 : 1000 dilution.
- Entrez GeneID:
- 4800
- Gene Name:
- NFYA
- Gene Alias:
- CBF-A,CBF-B,FLJ11236,HAP2,NF-YA
- Gene Description:
- nuclear transcription factor Y, alpha
- Omim ID:
- 189903
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq
- Other Designations:
- CAAT-box DNA binding protein subunit A,CCAAT-binding transcription factor subunit B,HAP2 CCAAT-binding protein,OTTHUMP00000016365,Transcription factor NF-Y, A subunit
- Gene Pathway