分子量：Calculated MW: 43kDa/45kDa
Observed MW: 45kDa

细胞定位：Secreted

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.