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上海信裕生物科技有限公司
API5抗体

API5抗体

商家询价

产品名称： API5抗体

英文名称： API5Antibody

产品编号： XY25689-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 API5抗体

Applications
In-house applications ELISA, IHC, WB, IF     Application not tested? Please see our Guarantee.
Species specificity Human, Mouse; other species not tested.
Images
Prev12NextView more validation data
  • 25689-1-AP;HepG2 cellsHepG2 cells were subjected to SDS PAGE followed by western blot with 25689-1-AP( API5 Antibody) at dilution of 1:300
  • 25689-1-AP;human pancreas tissueImmunohistochemistry of paraffin-embedded human pancreas tissue slide using 25689-1-AP( API5 Antibody) at dilution of 1:50 (under 10x lens)
  • 25689-1-AP;human pancreas tissueImmunohistochemistry of paraffin-embedded human pancreas tissue slide using 25689-1-AP( API5 Antibody) at dilution of 1:50 (under 40x lens)
  • 25689-1-AP;HepG2 cellsImmunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using 25689-1-AP( API5 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HepG2 cells, HeLa cells, MCF-7 cells, NIH/3T3 cells
Positive IHC detected in Human pancreas tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500
 API5抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen API5 fusion protein Ag22524 Full name Apoptosis inhibitor 5
Calculated molecular
weight		 58 kDa Observed molecular 
weight		 50-55 kDa
GenBank accession 
number		 BC017709 API5抗体 Gene ID (NCBI) 8539
Gene symbol API5 Synonyms AAC 11, AAC11, Antiapoptosis clone 11 protein, API 5, API5, apoptosis inhibitor 5, FIF, Protein XAGL
Background

The human gene API5 encodes the protein Apoptosis inhibitor 5. This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of chemotherapeutic drugs. Diseases associated with API5 include colon adenocarcinoma, and cervical cancer. API5抗体

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