Anti-RNF19B/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-RNF19B/FITC Conjugated抗体

Anti-RNF19B/FITC Conjugated抗体

商家询价

产品名称: Anti-RNF19B/FITC Conjugated抗体

英文名称: Anti-RNF19B/FITC

产品编号: YB--9246R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-RNF19B/FITC Conjugated抗体

产品编号 YB-9246R-FITC
英文名称 Anti-RNF19B/FITC
中文名称 FITC标记的环指蛋白19B抗体
别    名 E3 ubiquitin-protein ligase RNF19B; IBR domain containing 3; IBR domain-containing protein 3; IBRDC3; Natural killer lytic-associated molecule; NKLAM; RING finger protein 19B; RN19B_HUMAN; rnf19b.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  t-淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 78kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RNF19B
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.

Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. 

Subunit:
Interacts with UBE2L3, UBE2L6 and UCKL1. 

Subcellular Location:
Cytoplasmic granule membrane.

Tissue Specificity:
Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in natural killer cells

Similarity:
Belongs to the RBR family. RNF19 subfamily. 
Contains 1 IBR-type zinc finger. 
Contains 2 RING-type zinc fingers. 

Database links:

Entrez Gene: 127544 Human

Omim: 610872 Human

SwissProt: Q6ZMZ0 Human

Unigene: 591504 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicationS