ELA2 (Human) ELISA Kit
产品名称: ELA2 (Human) ELISA Kit
英文名称: ELA2 (Human) ELISA Kit
产品编号: KA1842
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- ELA2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human ELA2.
- Limit of Detection:
- 0.15 ng/mL
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C.
- Quality Control Testing:
- Standard Curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
- Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Cell Culture Supernatant, Milk, Plasma, Saliva, Serum, Urine
- Sample Volume:
- 50 uL
- Label:
- Biotin-conjugate
- Detection Method:
- Colorimetric
- Intra-Assay:
- 5.1%
- Inter-Assay:
- 7.4%
- Spiking Recovery:
- 96%
- Regulation Status:
- For research use only (RUO)
- Application Image
- Quantification
- Entrez GeneID:
- 1991
- Gene Name:
- ELA2
- Gene Alias:
- GE,HLE,HNE,NE,PMN-E
- Gene Description:
- elastase 2, neutrophil
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq
- Other Designations:
- bone marrow serine protease,granulocyte-derived elastase,leukocyte elastase,medullasin,polymorphonuclear elastase
- Gene Pathway