TLR2 monoclonal antibody, clone TL2.1
产品名称： TLR2 monoclonal antibody, clone TL2.1
英文名称： TLR2 monoclonal antibody, clone TL2.1
产品编号： MAB0067
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant TLR2.
- Immunogen:
- Recombinant protein corresponding to full length human TLR2.
- Host:
- Mouse
- Reactivity:
- Dog, Human
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid.
Prabha C, Rajashree P, Sulochana DD.Immunol Lett. 2008 Apr 15;117(1):26-34. Epub 2007 Dec 3.
- 2.
- Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Wong CK, Cheung PF, Ip WK, Lam CW.Am J Respir Cell Mol Biol. 2007 Jul;37(1):85-96. Epub 2007 Mar 1.
- 3.
- Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes.
Menzies BE, Kenoyer A.Infect Immun. 2006 Dec;74(12):6847-54. Epub 2006 Sep 5.
- 4.
- High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production.
Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, Koski G, Czerniecki BJ.Surgery. 2006 Aug;140(2):170-8.
- 5.
- A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.
Shimizu T, Kida Y, Kuwano K.J Immunol. 2005 Oct 1;175(7):4641-6.
- Applications
- Entrez GeneID:
- 7097
- Gene Name:
- TLR2
- Gene Alias:
- CD282,TIL4
- Gene Description:
- toll-like receptor 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
- Other Designations:
- toll/interleukin 1 receptor-like 4
- Gene Pathway
- Related Disease
- Acute Disease
- Aggressive Periodontitis
- Agricultural Workers' Diseases
- Amyloidosis
- Arthritis, Reactive
- Arthritis, Rheumatoid
- Aspergillosis
- Aspergillosis, Allergic Bronchopulmonary
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Bacteremia
- Bacterial Infections
- Bacteriuria
- Behcet Syndrome
- Birth Weight
- Breast Neoplasms
- Bronchial Hyperreactivity