CYP24A1 monoclonal antibody (M07), clone 1F8
产品名称: CYP24A1 monoclonal antibody (M07), clone 1F8
英文名称: CYP24A1 monoclonal antibody (M07), clone 1F8
产品编号: H00001591-M07
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant CYP24A1.
- Immunogen:
- CYP24A1 (NP_000773, 415 a.a. ~ 514 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLHSGTLVPSRELPIAFCQR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of CYP24A1 expression in transfected 293T cell line by CYP24A1 monoclonal antibody (M07), clone 1F8.
Lane 1: CYP24A1 transfected lysate (Predicted MW: 11.11 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged CYP24A1 is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 1591
- GeneBank Accession#:
- NM_000782
- Protein Accession#:
- NP_000773
- Gene Name:
- CYP24A1
- Gene Alias:
- CP24,CYP24,MGC126273,MGC126274,P450-CC24
- Gene Description:
- cytochrome P450, family 24, subfamily A, polypeptide 1
- Omim ID:
- 126065
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- 1,25-@dihydroxyvitamin D3 24-hydroxylase,24-OHase,OTTHUMP00000031314,cytochrome P450 family 24 subfamily A polypeptide 1,cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase),exo-mitochondrial protein,vitamin D 24-hydroxylase
- Related Disease
- Adenocarcinoma
- Asthma
- Asthma
- Breast cancer
- Breast Neoplasms
- Calcinosis
- Cardiovascular Diseases
- Colon cancer
- Colonic Neoplasms
- Coronary Artery Disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hypercalcemia
- Hypercalciuria
- Hypertension