PTGES polyclonal antibody
产品名称： PTGES polyclonal antibody
英文名称： PTGES polyclonal antibody
产品编号： PAB0130
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant purified 6-His mPGES-1.
- Immunogen:
- Recombinant protein corresponding to human purified 6-His mPGES-1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat, Sheep
- Form:
- Lyophilized
- Storage Buffer:
- Lyophilized from serum
- Storage Instruction:
- Store at -20°C on dry atmosphere.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:10000)
Immunohistochemistry (Frozen sections) (1:6000)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Selective PGE2 suppression impairs colon carcinogenesis and modifies local mucosal immunity.
Nakanishi M, Menoret A, Tanaka T, Miyamoto S, Montrose DC, Vella A, Rosenberg DW.Cancer Prev Res (Phila). 2011 May 16. [Epub ahead of print]
- Application Image
- Western Blot (Recombinant protein)
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Entrez GeneID:
- 9536
- Gene Name:
- PTGES
- Gene Alias:
- MGC10317,MGST-IV,MGST1-L1,MGST1L1,MPGES,PGES,PIG12,PP102,PP1294,TP53I12,mPGES-1
- Gene Description:
- prostaglandin E synthase
- Omim ID:
- 605172
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq
- Other Designations:
- MGST1-like 1,OTTHUMP00000022345,glutathione S-transferase 1-like 1,microsomal glutathione S-transferase 1-like 1,microsomal prostaglandin E synthase-1,p53-induced apoptosis protein 12,p53-induced gene 12,tumor protein p53 inducible protein 12
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Brain Ischemia
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Colorectal Neoplasms
- Connective Tissue Diseases
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent
- Edema
- Esophageal Neoplasms
- Fetal Diseases
- Genetic Predisposition to Disease
- Hypertension