PeproTech重组人GDF-3 (Animal Free) 20ug
产品名称: PeproTech重组人GDF-3 (Animal Free) 20ug
英文名称: Recombinant Human GDF-3
产品编号: AF-120-22
产品价格: 0
产品产地: 美国
品牌商标: PeproTech
更新时间: null
使用范围: null
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- 邮编 : 215123
- 所在区域 : 江苏
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Recombinant Human GDF-3
Catalog Number:AF-120-22Synonyms:Growth/Differentiation, Factor-3, Vgr-2Description:GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains. Manufactured using all non-animal reagents.AA Sequence:AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCGSource:E.coliPurity:Greater than 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/ml.Research Interests:Country of Origin:USAResearch Use Only. Not for use in diagnostic or therapeutic procedures.